Claudin-4 Identified as the Docking Point for a Colon-Damaging Bacterial Toxin
Researchers found that B. fragilis toxin binds to claudin-4, then built a molecular decoy that protected mice from toxin-induced colon damage.
Type VI Retrons Use DNA to Trigger a Bacterial Self-Destruct Defense
A newly mapped bacterial defense turns DNA into a toxin-production switch, revealing a distinct route to viral containment and new research possibilities.
Vitamin A and Thyroid Hormones May Shape the Human Retina Before Birth
Human retinal organoids suggest some early blue-sensitive cells become red and green cones, revising a decades-old model of central vision development.
Hidden Aggressive Cells May Explain Risk in Childhood Rhabdomyosarcoma
Single cell analysis found aggressive cancer cells in some rhabdomyosarcoma tumors that lack the usual high risk genetic marker.
Chronic Back Pain Flare-Ups Activate Brain Network Tied to the Self
A study of 114 people with chronic low back pain found movement-triggered flares activate the brain’s default mode network, unlike acute pain.
Two-Year Trial Finds Diet Drinks Don’t Undermine Weight Loss
A 104-week trial found similar weight loss with diet drinks and water, while sugar intake fell slightly more among participants drinking low-calorie beverages.
Sauna Session Temporarily Increases Circulating Immune Cells, Study Finds
A study of 51 adults found that sauna bathing with a brief cold shower briefly raised white blood cell counts, which returned to baseline within 30 minutes.
Inulin Trial Links Gut Health to Lower Knee Arthritis Pain and Better Strength
A six-week trial found that inulin reduced knee osteoarthritis pain and pain sensitivity, while researchers saw links between gut hormones and grip strength.
Testosterone 21 Combines Four Ingredients in a Twice-Daily Men’s Supplement
Hi-Tech Pharmaceuticals’ Testosterone 21 pairs four ingredients with a two-tablet, twice-daily routine and the company’s Cyclosome delivery system.
Rising U.S. Health Care Costs Push Families to Skip Care and Take on Debt
Rising premiums, deductibles, and medical bills are forcing people across the U.S. to delay care, ration medication, and take on debt.
Why Weight-Loss Plans Often Stall: Nine Forces That Slow Progress
Weight loss changes appetite, energy use and daily habits. Those shifts help explain why early progress can stall and why strict plans are hard to sustain.
Ear Nerve Stimulation Shows Promise for Severe, Hard-to-Control Hypertension
A small home-use device didn’t lower blood pressure across the full trial, but planned subgroup results point to a possible benefit in more severe cases.
U.S. Health System Trails Peers on More Quality Measures Than It Leads
The U.S. spends nearly twice as much per person on health care as peer nations, yet falls behind on more quality measures than it surpasses.
Texas A&M Study Finds Creatine May Support Muscle Gains Without Structured Exercise
In a 12-week study of adults aged 45 to 65, creatine users gained lean tissue with or without supervised exercise, with larger gains alongside training.
Personalized Magnetic Brain Stimulation Earns FDA Clearance for PTSD
Wave Neuroscience reports promising PTSD trial results for personalized magnetic stimulation, though full findings are still awaiting public release.